ProCore is developing a cell-based product for fracture healing.
This product is based on autologous vascular promoting cells that are isolated from a peripheral blood sample. The isolated cells are subsequently delivered and localized to the site of injury using CellMate™, ProCore’s proprietary biocompatible, injectable hydrogel. Local delivery leads to more effective cellular action, resulting in accelerated bone repair.
POC in vivo:
The therapeutic potential of this cell-based product for non-union or delayed union fractures, was tested in several models in both small and large animals. In all studies, a significant improvement in fracture healing was observed in those animals receiving ProCore’s product. In no instance was there any issue of safety or toxic effect.